Paper: arXiv 2406.15867
Authors: Thomas Cook, Patrick Flaherty
Abstract
Experimentation involves risk. The investigator expends time and money in the pursuit of data that supports a hypothesis. In the end, the investigator may find that all of these costs were for naught and the data fail to reject the null. Furthermore, the investigator may not be able to test other hypotheses with the same data set in order to avoid false positives due to p-hacking. Therefore, there is a need for a mechanism for investigators to hedge the risk of financial and statistical bankruptcy in the business of experimentation. In this work, we build on the game-theoretic statistics framework to enable an investigator to hedge their bets against the null hypothesis and thus avoid ruin. First, we describe a method by which the investigator’s test martingale wealth process can be capitalized by solving for the risk-neutral price. Then, we show that a portfolio that comprises the risky test martingale and a risk-free process is still a test martingale which enables the investigator to select a particular risk-return position using Markowitz portfolio theory. Finally, we show that a function that is derivative of the test martingale process can be constructed and used as a hedging instrument by the investigator or as a speculative instrument by a risk-seeking investor who wants to participate in the potential returns of the uncertain experiment wealth process. Together, these instruments enable an investigator to hedge the risk of ruin and they enable a investigator to efficiently hedge experimental risk.
Complexity vs Empirical Score
- Math Complexity: 7.5/10
- Empirical Rigor: 3.0/10
- Quadrant: Lab Rats — theoretically deep, empirically untested
Why this score: The paper introduces an innovative concept bridging game-theoretic statistics and financial derivative pricing to hedge hypothesis testing risk. While mathematically rigorous and conceptually novel, it relies heavily on theoretical derivations and basic toy simulations rather than extensive empirical backtesting with real-world statistical experimental data.
Research Flowchart
flowchart TD
A["Research Goal: Hedge financial & statistical risk in sequential experiments"] --> B["Base Input: Test Martingale Wealth Process"]
B --> C["Step 1: Calculate Risk-Neutral Price to Capitalize Test Martingale"]
C --> D["Step 2: Combine with Risk-Free Asset via Markowitz Portfolio Theory"]
D --> E["Step 3: Construct Derivative Contracts on the Test Martingale"]
E --> F["Outcomes: Avoid Experimenter Ruin & Enable Risk-Seeking Speculation"]
Cited References (114)
- Efficient Adaptive Experimental Design for Average Treatment Effect Estimation (2021) — link
- Statistical Inference with M -Estimators on Adaptively Collected Data (2021)
- Asymptotic normality for sums of dependent random variables (1972)
- Anytime-valid off-policy inference for contextual bandits (2024)
- Time-uniform, nonparametric, nonasymptotic confidence sequences (2021)
- Time-uniform central limit theory and asymptotic confidence sequences (2023) — link
- Estimating means of bounded random variables by betting (2023)
- Game-theoretic statistics and safe anytime-valid inference (2023) — link
and 106 more
- Adaptive Experimental Design Using the Propensity Score (2011)
- Experiment-as-Market: Incorporating Welfare into Randomized Controlled Trials (2018)
- Always Valid Inference: Continuous Monitoring of A/B Tests (2022)
- Sharp Finite-Time Iterated-Logarithm Martingale Concentration (2015) — link
- Sequential Nonparametric Testing with the Law of the Iterated Logarithm (2016)
- The Adaptive Doubly Robust Estimator and a Paradox Concerning Logging Policy (2021)
- Adaptive Doubly Robust Estimator from Non-stationary Logging Policy under a Convergence of Average Probability (2021) — link
- Some aspects of the sequential design of experiments (1952)
- Estimation of Regression Coefficients When Some Regressors Are Not Always Observed (1994)
- Randomization Analysis of Experimental Data: The Fisher Randomization Test Comment (1980)
- Comment: Which Ifs Have Causal Answers (1986)
- Double/debiased machine learning for treatment and structural parameters (2018)
- Statistical Methods Related to the Law of the Iterated Logarithm (1970)
- Confidence Sequences for Mean, Variance, and Median (1967)
- Multi-armed Bandit Experimental Design: Online Decision-making and Adaptive Inference (2023)
- On the near-optimality of betting confidence sets for bounded means (2023) — link
- Peeking at A / B Tests : Why It Matters, and What to Do about It (2017)
- CLIP - OGD : An Experimental Design for Adaptive Neyman Allocation in Sequential Experiments (2023)
- Asymptotic Efficiency Bounds for a Class of Experimental Designs (2022) — link
- Confidence intervals for policy evaluation in adaptive experiments (2021)
- CONOPT—a large-scale GRG code (1994)
- Controlling the false discovery rate: a practical and powerful approach to multiple testing (1995)
- The philosophy of multiple comparisons (1991)
- The Collected Works of John W. Tukey: Multiple Comparions (1994)
- $\alpha$-investing: a procedure for sequential control of expected false discoveries (2008)
- Generalized $\alpha$-investing: definitions, optimality results and application to public databases (2014)
- Online control of the false discovery rate with decaying memory (2017)
- Asynchronous Online Testing of Multiple Hypotheses. (2021)
- Online rules for control of false discovery rate and false discovery exceedance (2018)
- SAFFRON: an adaptive algorithm for online control of the false discovery rate (2018)
- A direct approach to false discovery rates (2002)
- Strong control, conservative point estimation and simultaneous conservative consistency of false discovery rates: a unified approach (2004)
- A framework for multi-a (rmed)/b (andit) testing with online fdr control (2017)
- A sequential algorithm for false discovery rate control on directed acyclic graphs (2019)
- Sequential Bonferroni methods for multiple hypothesis testing with strong control of family-wise error rates I and II (2012)
- Adaptive and dynamic adaptive procedures for false discovery rate control and estimation (2012)
- Adaptive linear step-up procedures that control the false discovery rate (2006)
- FDR control with adaptive procedures and FDR monotonicity (2011)
- Gene expression correlates of clinical prostate cancer behavior (2002)
- BagBoosting for tumor classification with gene expression data (2004)
- Decision theory: Principles and approaches (2009)
- Theory of games and statistical decisions (1979)
- Bayes and minimax solutions of sequential decision problems (1949)
- The weighted likelihood ratio, sharp hypotheses about chances, the order of a Markov chain (1970)
- Computing Bayes factors using a generalization of the Savage-Dickey density ratio (1995)
- Statistical decision theory and Bayesian analysis (2013)
- Contextual online false discovery rate control (2020)
- Neural FDR : Learning discovery thresholds from hypothesis features (2017)
- Transforming L1000 profiles to RNA-seq-like profiles with deep learning. (2022)
- Streaming Feature Selection Using Alpha-Investing (2005) — link
- Edgar R, Domrachev M, Lash AEGene Expression Omnibus: NCBI gene expression and hybridization array data repository. Nucl Acids Res 30: 207-210 (2002) — link
- The Power of Batching in Multiple Hypothesis Testing (2020)
- Dynamic Algorithms for Online Multiple Testing (2022)
- Online Multiple Hypothesis Testing (2023) — link
- onlineFDR: an R package to control the false discovery rate for growing data repositories (2019) — link
- Online multiple testing with e-values (2023) — link
- Probability and finance: it’s only a game! (2005)
- Testing by Betting: A Strategy for Statistical and Scientific Communication (2021)
- Test Martingales, Bayes Factors and p-Values (2011)
- Multiple Range and Multiple F Tests (1955)
- THE DISTRIBUTION OF RANGE IN SAMPLES FROM A NORMAL POPULATION, EXPRESSED IN TERMS OF AN INDEPENDENT ESTIMATE OF STANDARD DEVIATION (1939) — link
- The use of the ``studentized range’’ in connection with an analysis of variance (1952) — link
- The Analysis of Variance (1959) — link
- Comparing Individual Means in the Analysis of Variance (1949)
- Applications of the Theory of Error to the Interpretation of Trends (1929) — link
- Multiple Comparisons Among Means (1961)
- A Simple Sequentially Rejective Multiple Test Procedure (1979)
- A sharper Bonferroni procedure for multiple tests of significance (1988) — link
- A Course In Game Theory (2020) — link
- Zur Theorie der Gesellschaftsspiele (1928) — link
- The Compleat Strategyst: Being a Primer on the Theory of Games of Strategy (1986) — link
- Teoria statistica delle classi e calcolo delle probabilit `a (1936) — link
- The Mathematical Analysis of Logic (1847) — link
- On the Application of Probability Theory to Agricultural Experiments. Essay on Principles. Section 9. (1923)
- Statistical Methods for Research Workers (1925) — link
- On the Two Different Aspects of the Representative Method: The Method of Stratified Sampling and the Method of Purposive Selection (1934)
- On the Role of the Propensity Score in Efficient Semiparametric Estimation of Average Treatment Effects (1998)
- Efficient Estimation of Average Treatment Effects Using the Estimated Propensity Score (2003) — link
- The testing of statistical hypotheses in relation to probabilities a priori (1933)
- ON THE USE AND INTERPRETATION OF CERTAIN TEST CRITERIA FOR PURPOSES OF STATISTICAL INFERENCE PART I (1928) — link
- On Confidence Sequences (1976) — link
- Time-uniform Chernoff bounds via nonnegative supermartingales (2018) — link
- Admissible anytime-valid sequential inference must rely on nonnegative martingales (2022) — link
- Anytime-Valid Confidence Sequences in an Enterprise A/B Testing Platform (2023) — link
- Sequential Tests of Statistical Hypotheses (1945) — link
- Sequential Analysis (1947)
- Safe Testing (2024)
- E-values: Calibration, combination and applications (2021) — link
- Game-Theoretic Foundations for Probability and Finance (2019) — link
- Probability Theory (1977)
- Investment Science (2014) — link
- Auditing Fairness by Betting (2023) — link
- Théorie de la spéculation (1900) — link
- Rational Theory of Warrant Pricing (1965) — link
- The Pricing of Options and Corporate Liabilities (1973)
- Portfolio Selection (1952)
- Tight Concentrations and Confidence Sequences From the Regret of Universal Portfolio (2024) — link
- Statistical Decision Functions (1950)
- Sequential Estimation (1953) — link
- Asymptotically subminimax solutions of compound statistical decision problems, 1951 (1951)
- Stochastic Processes (1953)
- The Doctrine of Chances: Probabilistic Aspects of Gambling (2010)
- A New Interpretation of Information Rate (1956) — link
- Solving Stochastic Programming Problems with Risk Measures by Progressive Hedging (2018) — link
- Étude critique de la notion de collectif (1939)
- Cost-Aware Generalized $\alpha$-Investing for Multiple Hypothesis Testing (2024) — link
0 of 114 cited works are in the corpus; resolved via arXiv source bundles, Semantic Scholar and OpenAlex. Corpus-wide: 2518 linked papers.